Luton and Arsenal have not played each other in the top flight for 32 years ahead of Tuesday's clash.
Mikel Arteta's Premier League table toppers come into the fixture two points clear after easing past Wolves 2-1 at the Emirates on Saturday, while the hosts remain two points clear of the relegation zone following their 3-1 defeat at Brentford.
The two sides are preparing to do battle for the first time since 1991 - so, here's all you need to know.
What time does Luton vs Arsenal kick-off?
Location: Luton
Stadium: Kenliworth Road
Date: Tuesday, December 5
Kick-off: 815pm
Referee: Samuel Barrott
How to watch Luton vs Arsenal on TV and live stream:
UK: Amazon Prime
US: Peacock
Canada: fuboTV Canada
Arsenal team news:
Takehiro Tomiyasu limped off injured during Saturday's clash with Wolves, with Mikel Arteta saying the player would be asssed. With this clash coming fast on the heels of the weekend's victory, the Gunners Japanese defender will miss the match, with Ben White being drafted in at right-back.
Jurrien Timber, Fabio Vieira, Thomas Partey and Emile Smith Rowe all remain out.
Luton team news
Rob Edwards' side could be without talisman Tom Lockyer after the club captain was forced off against Brentford. Teden Mengi is another doubt from the game.
Loanee Albert Sambi Lokonga will not be able to face his parent club, but would be unlikely to feature due to fitness issues
Arsenal predicted lineup vs Wolves (4-3-3):
Raya; White, Saliba, Gabriel, Zinchenko; Rice, Odegaard, Havertz; Saka, Jesus, Trossard.
Luton vs Arsenal Head to Head:
The first match in this fixture was played back in 1897, which resulted in a 2-0 victory in Bedfordshire for Woolwich Arsenal.
The last time the teams met was Boxing Day, 1991, when The Hatters beat the Gunners 1-0.
In total the teams have played 48 times, with Arsenal winning 27, 11 draws and 10 defeats to Luton.